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  1. 11 hours ago · The developmental morphogenesis of complex tissues requires the coordinated action of distinct cell behaviors (Gumbiner, 1996).In the mammalian kidney, the induction of mesenchymal nephron progenitor cells (NPCs), which initiates a nephrogenic developmental program, is coupled to the establishment of an epithelial nephron precursor, the renal vesicle (RV; McMahon, 2016).