Frank Cooper
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The blood–brain barrier ( BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1] .
17 Apr 2023 · Your blood-brain barrier (BBB) is a filtering layer of cells surrounding blood vessels in most areas of your brain. It’s a critical line of defense, keeping most harmful things out and most helpful things in.
6 Dis 2021 · The blood-brain barrier (BBB) is a semipermeable and extremely selective system in the central nervous system of most vertebrates, that separates blood from the brain's extracellular fluid.
25 Mei 2023 · Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood.
17 Mac 2023 · The blood-brain barrier (BBB), first described by Paul Ehlrich (1885), is a highly selective semi-permeable membrane between the blood and brain interstitium. This unique barrier allows cerebral blood vessels to regulate the movement of molecules and ions between the blood and the brain.
18 Nov 2020 · The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function. Thus, the functional and structural integrity of the BBB is pivotal to maintain the homeostasis of the brain microenvironment.
The physiological barrier is coordinated by a series of physical, transport, and metabolic properties possessed by the brain endothelial cells (ECs) that form the walls of the blood vessels. These properties are regulated by interactions between different vascular, perivascular, immune, and neural cells. Understanding how these cell populations ...
