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  1. What's Up, Doc? is a 1972 American screwball comedy film directed by Peter Bogdanovich and starring Barbra Streisand and Ryan O'Neal. It was intended to pay homage to comedy films of the 1920s, 1930s, and 1940s, especially Bringing Up Baby and Warner Bros. Bugs Bunny cartoons.

  2. Mar 10, 1972 · What's Up, Doc?: Directed by Peter Bogdanovich. With Barbra Streisand, Ryan O'Neal, Madeline Kahn, Kenneth Mars. The accidental mix-up of four identical plaid overnight bags leads to a series of increasingly wild and wacky situations.

  3. Peter Bogdanovich's "What's Up, Doc?" is billed as a wacky screwball comedy with absolutely no redeeming social importance, and I guess that's the most accurate billing so far this year. It has to do with four guests who check into a hotel on the same day, with identical red plaid overnight bags.

  4. The accidental mix-up of four identical plaid overnight bags leads to a series of increasingly wild and wacky situations. Two researchers have come to San Francisco to compete for a research grant in music.

  5. What's Up, Doc? -- (1972) -- (Original Trailer) Director Peter Bogdanovich joins stars Barbra Streisand and Ryan O'Neal for this full-on tongue in cheek trailer for the 1972 comedy hit What's Up, Doc?, also the feature debut of Madeline Kahn.

  6. A screwball comedy. Remember them? Overview. The accidental mix-up of four identical plaid overnight bags leads to a series of increasingly wild and wacky situations. Peter Bogdanovich. Director, Story. Buck Henry. Screenplay. Robert Benton. Screenplay. David Newman. Screenplay.

  7. In Theaters At Home TV Shows. Two researchers have come to San Francisco to compete for a research grant in music. The man seems a bit distracted, and that was before he met a strange woman who ...