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Sep 27, 2022 · Bullous pemphigoid (BUL-us PEM-fih-goid) is a rare skin condition that causes large, fluid-filled blisters. They develop on areas of skin that often flex — such as the lower abdomen, upper thighs or armpits.
Bullous pemphigoid is a rare skin condition that causes blisters on your skin. It’s an autoimmune disease. Certain medications may trigger bullous pemphigoid, but healthcare providers aren’t sure exactly what causes it.
Bullous pemphigoid is the most common form of autoimmune subepidermal blistering disease. Treatment for bullous pemphigoid is usually needed for several years. In many cases, the pemphigoid eventually completely clears up, and the treatment can be stopped.
Mar 2, 2023 · Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disorder, representing 80% of subepidermal immunobullous cases.[1] Bullous pemphigoid most commonly affects elderly patients between the ages of 60 to 80 years. While the clinical presentation of bullous pemphigoid is broad, the immunobullous skin disorder characteristically presents with tense bullae and intense ...
Bullous pemphigoid is a chronic disease, which means it lasts longer than six weeks. For many people, this disease lasts for months or years. As older blisters open and crust over, new blisters can appear.
Bullous pemphigoid (a type of pemphigoid) is an autoimmune pruritic skin disease that typically occurs in people aged over 60, that may involve the formation of blisters in the space between the epidermal and dermal skin layers.It is classified as a type II hypersensitivity reaction, which involves formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane ...
Feb 22, 2023 · This information explains what bullous pemphigoid is and how to treat it. Bullous pemphigoid (BUL-us PEM-fih-goid) is a rare skin condition. It causes large fluid-filled blisters to form on your skin.
Test results help differentiate bullous pemphigoid from pemphigus vulgaris, linear IgA disease, erythema multiforme, drug-induced eruptions, mucous membrane pemphigoid, paraneoplastic pemphigoid, dermatitis herpetiformis, and epidermolysis bullosa acquisita. If bullous pemphigoid is suspected, skin biopsy is done for histology and direct immunofluorescence testing.
Clinical trials. Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.. Lifestyle and home remedies. If you have bullous pemphigoid, you can help take care of your condition with the following self-care strategies:
Bullous pemphigoid occurs more often in patients > age 60 but can occur in children. IgG autoantibodies bind to certain hemidesmosomal antigens (BPAg1 [BP230], BPAg2 [BP180]), resulting in the activation of complement to form a subepidermal blister (see figure Skin cleavage levels in pemphigus and bullous pemphigoid Skin cleavage levels in pemphigus and bullous pemphigoid ).
