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May 23, 2024 · UNASYN, ampicillin sodium/sulbactam sodium parenteral combination, is available as a white to off-white dry powder for reconstitution. UNASYN dry powder is freely soluble in aqueous diluents to yield pale yellow to yellow solutions containing ampicillin sodium and sulbactam sodium equivalent to 250 mg ampicillin per mL and 125 mg sulbactam per mL.
Adult including elderly & childn ≥30 kg 375-750 mg bd. Uncomplicated gonorrhea 2.25 g as single dose w/ concomitant probenecid 1 g to prolong plasma conc of Unasyn.Childn <30 kg 25-50 mg/kg daily in 2 divided doses.
Unasyn side effects. Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).. Unasyn may cause serious side effects. Call your doctor at once if you have: ...
Medscape - Indication-specific dosing for Unasyn, (ampicillin-sulbactam), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
Adult 1.5-12 g daily in divided doses every 6-8 hr. Max: Sulbactam 4 g daily.Less severe infections May be treated every 12 hr. Prophylaxis of surgical infections 1.5-3 g at anesth induction, may be repeated every 6-8 hr. Uncomplicated gonorrhoea 1.5 g as single dose w/ concomitant probenecid 1 g to prolong plasma conc of Unasyn.Childn, infant, neonate 150 mg/kg daily in divided doses every 6 ...
Jun 25, 2024 · UNASYN may be administered by either the IV or the IM routes. For IV administration, the dose can be given by slow intravenous injection over at least 10–15 minutes or can also be delivered in greater dilutions with 50–100 mL of a compatible diluent as an intravenous infusion over 15–30 minutes.
Jan 11, 2024 · Indications. Ampicillin is a β-lactam antimicrobial, whereas sulbactam is a β-lactamase inhibitor. The combination of ampicillin and sulbactam demonstrates synergy in addressing bacterial strains resistant to ampicillin, thus providing broader coverage. Bacteria susceptible to ampicillin/sulbactam include Haemophilus influenzae, Escherichia coli, Acinetobacter, Klebsiella, Staphylococcus ...
KEY POINTS Ampicillin-sulbactam (Unasyn) is the combination of aminopenicillin ampicillin plus beta-lactamase inhibitor sulbactam Has activity versus Gram negatives (not Pseudomonas), Gram positives (not MRSA) and anaerobes Sulbactam has activity against Acinetobacter Adding sulbactam to ampicillin expands coverage to include Bacteroides fragilis, MSSA, and more Gram negative coverage Can work ...
Alcohol Warning (Not Advisable) Unasyn 375mg Tablet 10s (strip) is generally safe to be consumed with alcohol since there is no known interaction nor adverse reaction following consumption of Unasyn 375mg Tablet 10s (strip) and alcohol ever recorded.Alcohol may further accentuate the symptoms of gut disturbances caused by Unasyn 375mg Tablet 10s (strip).
Breastfeeding Warning (Limited Data) There is small traces of Unasyn 250mg/5ml Suspension 30ml detected in human breastmilk and limited data suggest that it is compatible to be used during lactation period.Excretion of Unasyn 250mg/5ml Suspension 30ml is known to be in small amount in human breast milk.
