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Jul 7, 2024 · Wake-up strokes occur when a person goes to bed feeling normal and wakes up with symptoms of a stroke. The key difference between wake-up strokes and other types of stroke is that the time of onset is unknown. This can delay emergency medical treatment and exclude wake-up stroke survivors from typical stroke treatments.
Mar 26, 2014 · Patients waking-up with symptoms of stroke represent a specific subgroup of stroke patients. In general, stroke is the second most common single cause of death and the most frequent cause of permanent disability in industrialized countries.
May 16, 2018 · WAKE-UP was an investigator-initiated, multicenter, randomized, double-blind, placebo-controlled clinical trial involving patients with an unknown time of onset of stroke. All the...
Wake-up stroke, defined as the situation where a patient awakens with stroke symptoms that were not present prior to falling asleep, represents roughly 1 in 5 acute ischemic strokes and remains a therapeutic dilemma.
Wake-up strokes (WUS) are strokes with unknown exact time of onset as they are noted on awakening by the patients. They represent 20% of all ischemic strokes.
Sep 4, 2008 · Detection of neurological symptoms of stroke on awakening (wake-up stroke) is a relatively common situation. A statewide survey of patients admitted with stroke into hospitals in California noted that 8% of the cases had symptoms on awakening. 1 Other groups have described higher frequencies.
Dec 6, 2023 · A wake-up stroke occurs when you go to sleep healthy, without any signs of a stroke, and wake up with stroke symptoms. When someone has a wake-up stroke, it’s difficult to know...
Jan 10, 2020 · The WAKE UP [41••] trial was a randomized, double-blind, placebo-controlled trial that enrolled stroke patients who either awoke with stroke symptoms or could not identify the time of symptom onset. Patients were imaged with MRI DWI and FLAIR sequencing and those with an acute stroke on DWI sequences but without any visible abnormality on ...
Jul 16, 2020 · Acute Ischemic Stroke. •. Treatment for patients with acute ischemic stroke is guided by the time from the onset of stroke, the severity of neurologic deficit, and findings on neuroimaging.
Oct 24, 2018 · With this information in mind, the investigators of the WAKE-UP stroke trial investigated whether patients with acute ischemic stroke who were last seen well more than 4.5 hours after hospital arrival, and who had a DWI/FLAIR mismatch, were more likely to have a good outcome at 90 days with alteplase as compared with placebo. 8 This was an ...
