Search results
Rhodanese is a mitochondrial enzyme that detoxifies cyanide (CN −) by converting it to thiocyanate (SCN −, also known as "rhodanate"). In enzymatology, the common name is listed as thiosulfate sulfurtransferase (EC 2.8.1.1). The diagram on the right shows the crystallographically-determined structure of rhodanese. It catalyzes the following ...
Rhodanese is a ubiquitous enzyme that catalyzes the conversion of cyanide to thiocyanate, and binds selenium and glutathione. Learn about its phylogenetic and tissue distribution, kinetics and mechanism of catalysis, and related topics in biochemistry and toxicology.
Jul 30, 2022 · Thiosulfate: cyanide sulfurtransferase (TST), also named rhodanese, is an enzyme widely distributed in both prokaryotes and eukaryotes, where it plays a relevant role in mitochondrial function.
Jun 14, 2015 · Rhodanese is the main enzyme in sulfur metabolism for cyanide detoxification. Sulfur metabolism is important not only in detoxification but also in anti-oxidative stress systems. As environmental radiation stresses were encountered, organisms developed resistance to environmental radiation.
Sep 1, 2012 · Mitochondrial bovine rhodanese is the best characterized rhodanese which is 293 amino acids long consisting of inactive N-terminal and catalytic C-terminal domain.
Jun 1, 2020 · Thiosulfate sulfurtransferase (TST, EC 2.8.1.1), also known as Rhodanese, is a mitochondrial enzyme which catalyzes the transfer of sulfur in several molecular pathways. After its initial identification as a cyanide detoxification enzyme, it was found that its functions also include sulfur metabolism, modification of iron‑sulfur clusters and ...
Jul 17, 2018 · To test if the putative rhodanese cDNAs encode proteins with rhodanese activity, we expressed them heterologously in E. coli in frame with the sequence for an N-terminal Strep tag.
