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Jun 26, 2024 · The emergence of new synthetic opioids and a record supply and demand of other drugs has compounded the impacts of the world drug problem, leading to a rise in drug use disorders and environmental harms, according to the World Drug Report 2024 launched by the UN Office on Drugs and Crime (UNODC) today.
3 days ago · Naloxone, which is given as a nasal spray or injection, works by seizing opioid receptors, kicking out opioids and taking their place. (Naloxone has no addictive properties of its own.) The researchers found that the new compound — known for now as compound 368 — binds next to naloxone on opioid receptors and helpfully holds naloxone in place.
3 days ago · A compound has been discovered that increases the potency and duration of action of naloxone, a drug used to reverse the effects of opioid overdoses — possibly opening up another way to save ...
3 days ago · Naloxone, one of two approved overdose reversal agents, is a key tool used by US health authorities for tackling the opioid epidemic. In California, the state government in April struck a deal ...
Jun 21, 2024 · Deaths from fentanyl far exceed overdoses from other opioids – nearly four times overdose deaths caused by prescription opioids (14,716) and heroin (5,871) in 2022. Are people seeking treatment for opioid addiction?
3 days ago · Naloxone has long been hailed as a life-saving drug in the face of the opioid epidemic. But its capacity to save someone from an overdose can be limited by the potency of the opioid — a person ...
Jun 17, 2024 · Opioid-related deaths in the US led to an estimated 3.1 million years of life lost in 2022 (38 years per death), compared to 2.0 million years lost in 2019. Relative to a scenario with no opioid mortality, we estimate that opioid-related deaths reduced life expectancy nationally by 0.67 years in 2022 vs 0.52 years in 2019.
