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Sep 21, 2024 · The global risks, benefits, and relevance of early-phases clinical trials participation for patients with hematological malignancies remain poorly evaluated. Patients and Methods. All early-phases clinical trials participations for patients with hematological malignancies, from 2008 to 2023, in a tertiary academic center in Europe, were reviewed.
Sep 5, 2024 · Women ≥18 years of age received inavolisib, palbociclib, and letrozole (Inavo + Palbo + Letro arm) or fulvestrant (Inavo + Palbo + Fulv arm) until unacceptable toxicity or disease progression. The primary objective was to evaluate safety or tolerability.
17 hours ago · What are the phases of a clinical trial? Explore the definitions of phase 1, 2, 3 and 4 clinical trials and learn how to find a trial that fits your needs.
Sep 10, 2024 · We present a first-in-human phase I clinical trial systemically administered B7-H3 chimeric antigen receptor (CAR) T cells for young patients with relapsed or refractory solid tumors.
Sep 4, 2024 · September 04, 2024. Results From First-in-Human Phase I Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients With Advanced Solid Tumors. Authors: Babar Bashir, MD, Judy S. Wang, MD, Gerald Falchook, MD, Elisa Fontana, MD, Hendrik-Tobias Arkenau, MD, Louise Carter, MBBS, PhD, Rachel Galot, MD, …
Sep 13, 2024 · The Phase I trial was designed to test the safety and tolerability of the immunotherapy, and secondary and tertiary objectives were to assess the radiographic and immunological responses. Eight...
