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2 days ago · Search strategy and selection criteria. We registered our protocol with PROSPERO (Registration Number: CRD42024500052).Electronic databases including PUBMED, EMBASE, Web of Science, and Cochrane Library were systematically searched from inception to 7 January 2024, to identify published RCTs employing probiotics, prebiotics, or synbiotics alone or in combination for the treatment of overweight ...
2 days ago · Background Healthy dietary patterns have been negatively associated with methylation-based measures of biological age, yet previous investigations have been unable to establish the relationship between them and biological aging assessed through blood chemistry-based clinical biomarkers. We sought to assess the associations of 4 dietary metrics with 4 measures of biological age. Methods Among ...
2 days ago · An active lifestyle is of key importance for reduction of obesity and inflammation, as well as circulating levels of adipokines. Therefore, the aim of our study was to assess the relationship of physical fitness with chronic inflammatory status, and to evaluate biomarkers useful in the analysis of adipose tissue dysfunction. Sixty-three older adults (69.6 ± 5.1 years) were allocated to a high ...
4 days ago · Periorbital aging typically manifests with dermatochalasis and depression of the upper eyelid. Blepharoplasty is a popular choice for addressing upper eyelid skin laxity but is not suitable for sunken eyelids. This study introduces an innovative approach for periorbital rejuvenation by addressing dermatochalasis and sunken upper eyelids concurrently in aging Asian women.
Sep 13, 2024 · KUALA LUMPUR (Sept 13): Hong Leong Asset Management Bhd, the fund management arm of Hong Leong Financial Group Bhd (KL: HLFG), on Friday announced the appointment of Chue Kwok Yan as its chief executive officer.
2 days ago · Wu et al. showed that infrapatellar fat pad MSCs protected AC and alleviated gait abnormalities via miR-100-5p-abundant exosomes by inhibiting mTOR pathway in osteoarthritis (52). Only one study on human articular chondrocytes revealed that UCMSCs-derived exosomes inhibited ROS generation and cell apoptosis through miR-100-5p/NOX4 regulation (53) .
4 days ago · Background/Objectives: Methyltransferase EZH2-mediated H3K27me3 is involved in liver inflammation and fibrosis, but its role in hepatic metabolic derangements is not yet clearly defined. We investigated if a high-fat diet (HFD) induced early changes in EZH2 expression and H3K27 me3 in the liver of mice. Methods: Five-week-old mice were fed an HFD or a low-fat diet (Control) for 2 weeks (2 W ...
