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  1. The Substance is a 2024 satirical body horror film written, directed, co-edited, and co-produced by Coralie Fargeat. It follows a fading celebrity (Demi Moore) who uses a black market drug that creates a much younger version of herself (Margaret Qualley) with unexpected side effects.

  2. The Substance: Directed by Coralie Fargeat. With Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark. A fading celebrity takes a black-market drug: a cell-replicating substance that temporarily creates a younger, better version of herself.

  3. Watch the official trailer for The Substance! In theaters September 20, 2024. A fading celebrity decides to use a black market drug, a cell-replicating substance that temp...more. Watch the ...

  4. With The Substance, you can generate another you: younger, more beautiful, more perfect. You just have to share time -- one week for one, one week for the other. A perfect balance of seven days...

  5. May 19, 2024 · The Substance is a showbiz satire which applies a Charlie Kaufman-ish science-fiction concept to the themes of Sunset Boulevard. Its heroine, played by Demi Moore,...

  6. A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

  7. Sep 6, 2024 · “The Substance” works as well as it does because of Moores unbridled performance as a woman struggling with self-hatred, societys treatment of her, and a newfound dependency on a miracle drug.

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