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  1. Dictionary
    frail
    /freɪl/

    adjective

    noun

    • 1. a woman. informal, dated US

    More definitions, origin and scrabble points

  2. health.usnews.com › best-senior-living › articlesWhat Is Frailty? | U.S. News

    Jun 20, 2024 · Frailty is a health condition characterized by physical decline, such as a loss of strength and mobility. Frailty most often affects older adults, though it can affect anyone,...

  3. 1 day ago · The prevalence of frailty and its association with all-cause mortality were studied among older adults aged 75 years and over who were followed for 2–8 years. Frailty, defined by the cumulative deficit method, utilized clinical data from the preceding 10-year period, comprising 28 chronic diseases and age-related health deficits.

  4. Jul 3, 2024 · Frailty is a complex, age-related clinical syndrome characterized by a decline in physiological capability across multiple organ systems and an increased susceptibility to stress [ 4 ].

  5. Jul 9, 2024 · The quality of being physically weak or fragile, or vulnerable to damage. In later use chiefly with reference to physical weakness or infirmity as a result of old age. Weakness in an abstract or immaterial sense; the state of being transient, subject to change, or vulnerable to harm. A moral failing; a particular weakness or character flaw.

  6. Jun 19, 2024 · Frailty is a common syndrome which occurs due to a combination of de-conditioning and acute illness on a background of existing functional decline that is often under recognised. Frailty is more common in females and the risk of frailty increases with age.

  7. Jul 8, 2024 · Frailty is defined as the loss of physiological reserve both at the physical and cellular levels, where systemic processes such as oxidative stress and inflammation contribute to physical decline. The newest “omics” technology and systems biology discipline, metabolomics, enables thorough characterisation of small-molecule metabolites in ...

  8. Jun 25, 2024 · Frailty profile was defined according to the five criteria proposed by Fried et al. 8 as (1) unintentional weight loss; (2) exhaustion; (3) low handgrip strength; (4) slow walking speed; and (5) physical inactivity. Three or more criteria defined frail, one or 2 criteria defined pre-frail, and absence of criteria defined non-frail. 8

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