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Jun 15, 2021 · Transplantation of MSCs-derived EVs (MSCs-EVs) affords a better neuroprotective against IS when compared with transplantation of MSCs alone. MSC therapy can prolong the treatment time window of ischemic stroke, and early administration within 7 days after stroke may be the best treatment opportunity.
Jun 15, 2021 · Chen et al. found that MSC treatment significantly increased bFGF in the ischemic border area of rats with middle cerebral artery occlusion, accompanied by a significant decrease of apoptotic cells in the ischemic border area .
Aug 6, 2020 · Chen B, Tao J, Lin Y, Lin R, Liu W, Chen L (2015) Electro-acupuncture exerts beneficial effects against cerebral ischemia and promotes the proliferation of neural progenitor cells in the cortical peri-infarct area through the Wnt/β-catenin signaling pathway.
Abstract. Stroke, a global disease with a high disability rate, has limited options for functional rehabilitation and results in an adverse impact on patients’ lives. In recent years, mesenchymal stem cells (MSCs) have become a new focus of treatment owing to their potential for neuroregeneration.
Nov 8, 2022 · Hou Z, Chen J, Yang H, Hu X, Yang F. microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis.
Mar 29, 2021 · Yinghan Guo , Yucong Peng , Hanhai Zeng , and Gao Chen Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China Correspondence should be addressed to Gao Chen; d-chengao@zju.edu.cn
Feb 9, 2021 · Zhang Q., Chen Z. W., Zhao Y. H., Liu B. W., Liu N. W., Ke C. C., et al. (2017). Bone marrow stromal cells combined with Sodium Ferulate and n-Butylidenephthalide promote the effect of therapeutic angiogenesis via advancing astrocyte-derived trophic factors after ischemic stroke.
