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  1. Annihilation is a 2018 science fiction horror thriller film written and directed by Alex Garland, loosely based on the 2014 novel of the same name by Jeff VanderMeer. It stars Natalie Portman, Jennifer Jason Leigh, Gina Rodriguez, Tessa Thompson, Tuva Novotny, and Oscar Isaac.

  2. Feb 23, 2018 · A biologist joins a secret expedition into a mysterious zone where the laws of nature don't apply. IMDb provides cast and crew information, user and critic reviews, trivia, goofs, quotes, and more for this adventure drama horror film.

  3. Feb 23, 2018 · A sci-fi film about a biologist (Natalie Portman) who ventures into a mysterious zone called The Shimmer, where she faces dangers and questions about her identity and reality. The film is praised for its visionary, unsettling, and disorienting style, but also criticized for its final act.

  4. Watch the official trailer for #Annihilation starring Natalie Portman, Jennifer Jason Leigh, Gina Rodriguez, Tessa Thompson, Tuva Novotny, and Oscar Isaac.

  5. Nov 13, 2023 · Alex Garland's film Annihilation works best when taken as a gigantic metaphor for cancer. We're unpacking and explaining what the movie might mean.

  6. Feb 23, 2018 · Annihilation backs up its sci-fi visual wonders and visceral genre thrills with an impressively ambitious -- and surprisingly strange -- exploration of challenging...

  7. Synopsis. At the U.S. government's Area X facility on a southern coast, cellular biology professor and former U.S. Army soldier Lena (Natalie Portman) undergoes a quarantined debriefing about an expedition into an anomaly called "the Shimmer", from which she and her husband are the only survivors.