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  1. Deep Blue Sea is a 1999 American science fiction horror film directed by Renny Harlin and starring Saffron Burrows, Thomas Jane, Samuel L. Jackson, Michael Rapaport, and LL Cool J. It is the first film of the film series by the same name.

  2. Synopsis. Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease. But there's an unexpected side effect: the sharks got smarter, faster, and more dangerous.

  3. Deep Blue Sea: Directed by Renny Harlin. With Thomas Jane, Saffron Burrows, Samuel L. Jackson, Jacqueline McKenzie. Searching for a cure to Alzheimer's disease, a group of scientists on an isolated research facility become the prey, as a trio of intelligent sharks fight back.

  4. On an island research facility, Dr. Susan McAlester (Saffron Burrows) is harvesting the brain tissue of DNA-altered sharks as a possible cure for Alzheimer's disease.

  5. Deep Blue Sea - Original Theatrical Trailer. Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease.

  6. A shark conservation biologist named Dr. Misty Calhoun, is hired in a consultory position for a non-public confidential project involving genetically-enhanced bull sharks. Funded by a pharmaceutical billionaire with questionable ethics, the mogul plans to medically market intelligence.

  7. Synopsis. In a remote underwater facility, doctors Susan McCallister ( Saffron Burrows) and Jim Whitlock ( Stellan Skarsgård) are doing research on Mako sharks to help in the re-activation of dormant human brain cells like those found in Alzheimer's disease patients.