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  1. Nov 15, 2021 · Findings show that despite a great degree of heterogeneity in the literature, progression of frailty is unquestionably affected by numerous risk and protective factors, with particular influence exhibited by social demographics, brain pathology, and physical comorbidities.

  2. Jun 2, 2020 · Thibeau, McDermott, McFall, Rockwood, and Dixon (2019) used a latent growth model to explore the frailty trajectory of 632 participants in the Victoria Longitudinal Study.

  3. Nov 10, 2021 · Objectives: to assess population frailty trajectories by age at death and to analyse whether the current level of the frailty index (FI) i.e. the most recent measurement or the person-specific rate of change is more predictive of mortality.

  4. Dec 12, 2022 · Frailty is an age-related clinical state associated with deterioration across multiple physiological systems and a leading cause of morbidity and mortality later in life. To understand how frailty develops and what causes its progression, longitudinal data with repeated frailty measurements are required.

  5. Jul 12, 2021 · Four trajectory classes identified: relatively stable (1), mild frail (2), moderate frail (3) and severely frail (4). The Y-axis depicts the frailty index scores (range 0 to 1) and x-axis follow-up time in years.

  6. Mar 27, 2024 · Four trajectories of frailty index among older people were identified: low frailty, progressive mild frailty, progressive moderate frailty and high frailty. Low subjective social status was associated with an increased risk of frailty independent of objective socioeconomic status and other factors.

  7. Jun 11, 2021 · frailty shows an upward trajectory with age, and higher levels increase the risk of mortality. However, it is less known whether the shape of frailty trajectories differs by age at death or whether the rate of change in frailty is associated with mortality.