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  1. The acute-phase response is the term given to the coordinated series of events that occur nonspecifically in response to infection, inflammation, or trauma. This response can be seen as the host's means of creating an inhospitable environment for the invading microbe.

  2. Acute-phase proteins (APPs) are a class of proteins whose concentrations in blood plasma either increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute-phase response).

  3. Oct 28, 2005 · The acute phase response (APR) is a prominent systemic reaction of the organism to local or systemic disturbances in its homeostasis caused by infection, tissue injury, trauma or surgery, neoplastic growth or immunological disorders (Gordon and Koy, 1985; Gruys et al., 1999 ).

  4. Aug 31, 2023 · The acute phase response is an innate body defense seen during acute illnesses and involves the increased production of certain blood proteins termed acute phase proteins.

  5. The acute phase response is a systemic reaction against infection or tissue injury, which involves fever, leukocytosis, increased vascular permeability and increased serum levels of acute phase proteins. Acute phase proteins are synthesized in the liver in response to increased levels of certain cytokines including IL-1, TNFα and IL-6.

  6. The acute phase response is the body's rapid attempt to restore homeostasis after tissue injury, infection, neoplastic growth, or immunological disturbance. Inflammation evokes a constellation of local and distant events that comprise the acute phase response.

  7. Nov 29, 2011 · The acute phase response or APR is a term given to a collective of reactions to tissue injury resulting from infection, trauma, neoplasia, inflammation, and stress. The response is formulated by a number of different acute phase proteins (APP) that vary in magnitude and type among animal species.