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  1. Mar 4, 2023 · Salt and pepper sign or pepper pot skull refers to multiple tiny well-defined lucencies in the calvaria caused by resorption of trabecular bone in hyperparathyroidism. There is a loss of definition between the inner and outer tables of the skull and a ground-glass appearance as well as spotty deossification.

  2. May 23, 2022 · The salt and pepper sign is used to refer to a speckled appearance of tissue on imaging. It is used in many contexts, but most commonly for the appearance of certain lesions on MRI, especially paragangliomas.

  3. The salt-and-pepper appearance is characterized by the presence of vitiligo-like depigmentation with perifollicular pigmentary retention. The rich capillary network surrounding the hair follicle preserves melanogenesis, and hence the retained perifollicular pigmentation in systemic sclerosis.[ 2 ]

  4. May 6, 2021 · The salt-and-pepper appearance is a vitiligo-like skin manifestation characterized by a coexistence of hyperpigmentation and hypopigmentation. 3 These skin changes can be found in the sclerotic area.

  5. Salt and pepper sign or pepper pot skull refers to multiple little well-defined lucencies in the calvarium induced by resorption of trabecular bone in hyperparathyroidism. There is a losing of definition between the inner and outer tables of the skull and a ground-glass appearance as well as spotty deossification.

  6. The salt and pepper appearance, first described in 1987 by Olsen et al, is a characteristic imaging feature of paragangliomas, found on T1 and T2 MRI sequences, reflecting its hypervascular nature (See Fig. 1 and Fig. 2).

  7. Oct 13, 2016 · It also results in secondary hyperparathyroidism causing increased bone turn over and decreased bone mass, manifested radiologically as a “salt and pepper” appearance in skull, subperiosteal resorption, bone cysts and lytic lesions.

  8. Sep 19, 2020 · Salt and pepper pigmentation clinically manifests as vitiligo-like depigmentation with perifollicular pigmentary retention. Clinically lesions can be confused with vitiligo, idiopathic guttate hypomelanoses (IGH) and lichen sclerosus et atrophicus (LSA).

  9. Oct 25, 2021 · The characteristic salt and pepper appearance was noted over forehead, upper chest and back (Figure 1). Serological markers were positive for anti-nuclear antibody (1:160 in Hep2 cell line) and anti-topoisomerase antibody.

  10. May 18, 2024 · The low-signal intensity areas (“pepper”) appear both on T1w and T2w images due to signal flow void artifacts arising from the high flow areas in blood vessels inside these highly vascularized tumors [ 2, 3, 4] (Fig. 2 a, b). Fig. 1. Mixture of salt and pepper. Full size image.

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