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The pertechnetate ion (/ p ər ˈ t ɛ k n ə t eɪ t /) is an oxyanion with the chemical formula TcO − 4 . It is often used as a convenient water-soluble source of isotopes of the radioactive element technetium (Tc).
Technetium-99m pertechnetate is preferred over radioiodine when the patient has recently received thyroid-blocking agents (such as iodinated contrast agents) or is unable to take medication orally or when the study must be completed in less than 2 hours.
Despite new molecular genetic insight into congenital hypothyroidism the 123 I or, preferably, 99m Tc-pertechnetate scan remains the most accurate test for the detection of ectopic thyroid tissue and the differential diagnosis between thyroid dysgenesis (60–70% of cases), athyreosis (10–30% of cases) and inherited disorders of thyroid ...
May 20, 2023 · Tc-99m pertechnetate (Na + 99m Tc O 4-) is one of the technetium radiopharmaceuticals used in imaging of thyroid, colon, bladder and stomach. Technetium ( 99m Tc) has eight oxidation states 6 , from -1 to +7; specifically, the oxidation state of technetium in the pertechnetate anion ( 99m TcO 4 - ) is +7.
Pertechnetate has a short physical half-life (6 hours), and imaging procedures can begin as soon as 20 minutes after administration because of its rapid uptake by the thyroid. Pertechnetate emits low-energy γ-particles (140 keV), has no β-emission, and gives the lowest radiation dose to the thyroid of all available scanning agents.
Sodium pertechnetate is the inorganic compound with the formula NaTcO 4. This colourless salt contains the pertechnetate anion, TcO − 4 that has slightly distorted tetrahedron symmetry both at 296 K and at 100 K while the coordination polyhedron of the sodium cation is different from typical for scheelite structure. The radioactive 99m Tc O −
Oct 14, 2021 · Pertechnetate | O4Tc- | CID 9543089 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Feb 28, 2024 · The number of pertechnetate salts has been extended for a majority of the elements of the periodic table. A systematic crystallographic study of their coordination and level of hydration gives insight into periodic trends. The picture shows the M−Otc bond lengths of all known pertechnetates.
Feb 28, 2024 · Group 12 of the periodic table served as an ideal candidate to study divalent metal pertechnetates across the triad of Zn, Cd and Hg, thus moving to 4d and 5d metal pertechnetates and allowing to investigate similarities and differences across periods and directly with alkaline earth pertechnetates.
Technetium-99m sodium pertechnetate is crucial for brain imaging, thyroid studies, and cancer detection through nuclear medicine.
