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  1. Jan 18, 2022 · Alpha-blockers work by partially blocking the way some cells in your body receive instructions. They do this by blocking alpha-receptors, which are found on cells in specific areas or organs in your body.

  2. www.mayoclinic.org › high-blood-pressure › in-depthAlpha blockers - Mayo Clinic

    Aug 22, 2023 · Alpha blockers are a type of blood pressure medicine. Alpha blockers lower blood pressure by keeping a hormone called norepinephrine from tightening the muscles in the walls of smaller arteries and veins. As a result, the blood vessels remain open and relaxed. This improves blood flow and lowers blood pressure.

  3. Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system.

  4. Jun 13, 2023 · Alpha-blockers are medicines that are mainly used to treat high blood pressure (hypertension) and problems with passing urine in men who have enlargement of the prostate gland. Prostate gland enlargement is also called benign prostatic hyperplasia (BPH).

  5. May 6, 2024 · Alpha blockers bind to and block alpha-1 receptors. They are mostly used to treat high blood pressure or symptomatic benign prostatic hypertrophy (BPH) because alpha-1 receptors are located in the smooth muscle lining blood vessels, in the prostate, and in the neck of the bladder.

  6. Jul 3, 2023 · Alpha-blockers are medications used in the management and treatment of essential hypertension, benign prostatic hyperplasia (BPH), and pheochromocytoma.

  7. May 3, 2024 · Alpha blockers block targets called alpha receptors, which are found in arteries and smooth muscle. Through their action, they keep the hormone adrenaline from exerting a tightening effect on the muscles and the smaller arterial and venous walls.

  8. Mar 10, 2022 · Alpha blockers (α-blockers) are a class of medications that block alpha receptors in the body. They are widely available as both generic and brand-name medications. They treat benign prostatic hyperplasia (BPH) by relaxing the smooth muscles in the bladder.

  9. Alpha blockers affect the sympathetic nervous system and work by inhibiting alpha receptors. Alpha receptors are of two types: alpha receptor 1 and alpha receptor 2. Alpha 1 receptors are present on the vascular smooth muscle of the skin, sphincters of the gastrointestinal system, kidney, and brain.

  10. Alpha-blockers used in treating essential hypertension are all highly selective for α 1 -adrenoceptors. Non-selective blockers are used during hypertensive crisis caused by elevated circulating catecholamines (pheochromocytoma). The following table compares different alpha-blockers that are presently used in patients.