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  1. Dec 1, 2019 · Abstract. Lucio phenomenon (LP) is a rare reactional state seen in cases of diffuse lepromatous leprosy. Lucio leprosy is a pure, primitive, and diffuse form of lepromatous leprosy. It is observed almost exclusively in Mexico and Central America and is considered a globally restricted phenomenon.

  2. Jan 23, 2020 · Lucio phenomenon is a potentially fatal leprosy reaction seen in pure, primitive, and diffuse form of lepromatous leprosy. It is a globally restricted phenomenon that occurs in Mexico and Costa Rica; however, sporadic cases have been reported elsewhere.

  3. Lucio's phenomenon is an unusual reaction seen almost exclusively in patients from the Caribbean and Mexico with diffuse lepromatous leprosy, especially in untreated cases. It is characterised by recurrent crops of large, sharply demarcated, ulcerative lesions, affecting mainly the lower extremities, but may generalise and become fatal as a ...

  4. Lucio phenomenon is a rare and severe form of lepra reaction that causes necrosis of the skin and subcutaneous tissue. It occurs in patients with lepromatous leprosy and is associated with high levels of inflammatory markers.

  5. Apr 28, 2021 · A 48-year-old man presented with fever and blistering skin lesions. Multiple acid-fast bacilli were detected on biopsy of the skin, and a diagnosis of Lucio’s phenomenon, a reaction that occurs...

  6. Lucio’s phenomenon is a rare manifestation among lepromatous patients with a rapid and severe evolution and high mortality. It is difficult to differentiate from ulcerative/necrotic...

  7. Feb 21, 2018 · Lucio’s phenomenon (LP) is a life-threatening medical emergency. LP is potentially disabling. LP means advanced stage of leprosy and generally occurs in areas of high bacillary load.

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