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  1. Dec 8, 2023 · Clinicians can consider starting early (≤48 hours after illness onset) empiric antiviral treatment of non-higher-risk outpatients with suspected influenza, based upon clinical judgment, including without an office visit. SARS-CoV-2 and other etiologies of acute respiratory illness should also be considered.

  2. Nov 1, 1998 · For the acyclovir versus placebo studies, Cox models were adjusted for age (continuous variable), sex (male vs. female), pain severity at presentation (≥ moderate vs. none or mild), and duration of prodromal symptoms (≥48 h vs. < 48 h). For the valacyclovir versus acyclovir studies, the same factors were fitted into each Cox model, but ...

  3. Acyclovir was initiated a median of 21 hours (3-407) after presentation in encephalitis cases, and a median of 11 hours (3-118) in HSE. The most common reason for delay was a failure to consider HSE in the differential diagnosis, despite suggestive clinical features. Where therapy was delayed in HSE patients, the decision to begin acyclovir was ...

  4. Jun 18, 2024 · Acyclovir is a synthetic nucleoside analogue active against herpesviruses. Acyclovir tablets are formulations of an antiviral drug for oral administration. Each 800-mg tablet of acyclovir contains 800 mg of acyclovir and the inactive ingredients corn starch, microcrystalline cellulose, magnesium stearate, and sodium starch glycolate. Each 400 ...

  5. Feb 16, 2024 · Antiviral treatment should be started as soon as possible, as it is most effective when started within 72 hours after the shingles rash appears. After this time, antiviral medications may still be helpful if new blisters are appearing. Three antiviral drugs are used to treat shingles: Acyclovir (brand name: Zovirax)

  6. Jul 20, 2021 · Adult dosage (ages 18–64 years) Shingles typical dosage: 800 mg every 4 hours, five times per day for 7–10 days. Genital herpes: Typical initial dosage: 200 mg every 4 hours, five times per ...

  7. Clinically, the acute kidney injury seen with acyclovir is characterized by a decline in renal function within 24 to 48 h after drug initiation. Although acute kidney injury is typically asymptomatic, the acute kidney injury associated with acyclovir can be associated in rare cases with flank or abdominal pain. 5