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  1. We have highlighted the usefulness and strengths of SBE, but some limitations exist and should be kept in mind in our daily practice. First, while SBE is a valuable quantitative estimate of metabolic acid–base derangements, it does not provide any …

  2. Base Excess. Base excess (BE) refers to the difference between the observed and the normal buffer base concentration or, expressed differently, the amount of acid or base required to return the pH to 7.4 in the setting of a normal Paco2. 124 The BE is commonly derived from nomograms.

  3. Base excess introduced by Siggaard-Andersen in 1960 is introduced as an answer to the forty-year-long quest for a reliable, stand-alone marker of metabolic acidosis/alka-losis, independent from co-existing respiratory derangements, and able to quantify the severity of the disorder.

  4. Base excess can either be expressed for whole blood— BE(B), which does not consider the interaction of blood with the interstitial uid, or for the entire extracellular uid—BE(ecf), also called standard BE (SBE). e SBE calculation uses the same equation but considers a lower concentration of hemoglobin (either 1/3 of the actu-

  5. en.wikipedia.org › wiki › Base_excessBase excess - Wikipedia

    Base excess is defined as the amount of strong acid that must be added to each liter of fully oxygenated blood to return the pH to 7.40 at a temperature of 37°C and a pCO 2 of 40 mmHg (5.3 kPa). [2] A base deficit (i.e., a negative base excess) can be correspondingly defined by the amount of strong base that must be added.

  6. Apr 11, 2018 · Use of Base Excess. To diagnose an acid–base disorder, a three-step approach is feasible with the base-excess method. The first step is to evaluate standard base excess in relation to pH and P ...

  7. May 1, 2001 · Base excess (BE) introduced by Siggaard-Andersen in 1960 as an answer to the forty-year-long quest for a reliable, stand-alone marker of metabolic acidosis/alka-losis, independent from co-existing …