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5 days ago · Cell cycle is the name we give the process through which cells replicate and make two new cells. Cell cycle has different stages called G1, S, G2, and M. G1 is the stage where the cell is preparing to divide.
4 days ago · Eukaryotes have a life cycle that involves sexual reproduction, alternating between a haploid phase, where only one copy of each chromosome is present in each cell, and a diploid phase, with two copies of each chromosome in each cell.
1 day ago · Paul Nurse discusses how a 1971 paper by Culotti and Hartwell inspired him to investigate the cell cycle in fission yeast, and how these genetics studies led to the discovery of cyclin-dependent ...
2 days ago · Gutierrez-Morton et al. demonstrate cell-cycle-regulated nucleolar localization and protein abundance of Tof2, a SUMO substrate that anchors Cdc14 phosphatase to the nucleolus. Tof2 polySUMOylation triggers its ubiquitination by STUbL, extraction by Cdc48, and degradation by the proteasome, which promotes the nucleolar release of Cdc14 for mitotic exit.
4 days ago · This study revealed that cell cycle processes were enriched in E2/P4-treated infertile endometrial organoids as compared to fertile organoids. This could reflect persistently higher proliferative activity of the endometrial epithelial cells in differentiated infertile organoids compared to fertile organoids.
1 day ago · Cytokinetic abscission marks the final stage of cell division, during which the daughter cells physically separate through the generation of new barriers, such as the plasma membrane or cell wall. While the contractile ring plays a central role during cytokinesis in bacteria, fungi and animal cells, the process diverges in Apicomplexa. In Toxoplasma gondii, two daughter cells are formed within ...
1 day ago · Metaphase is a stage during the process of cell division (mitosis or meiosis). Normally, individual chromosomes are spread out in the cell nucleus. During metaphase, the nucleus dissolves and the cell’s chromosomes condense and move together, aligning in the center of the dividing cell.
