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2 days ago · The illustration demonstrates the effect of long-term treatment with finasteride, which is more effective in alleviating depression and microglia complexity. Both long-term treatment with finasteride and short-term treatment with finasteride followed by withdrawal alleviated anxiety-like behaviors, ameliorated metabolic disturbances, reduced ...
4 days ago · Controversy exists regarding whether finasteride may cause long-term sexual side effects even after discontinuation of the medication. 6 Many studies have been limited by selection bias, recall bias, or lack of control for confounding variables—specifically causes of erectile dysfunction such as vascular disease, diabetes, depression, and ...
4 days ago · The full mechanism of action for the anti-inflammatory effects of SSRIs is not fully known. However, there is evidence for various pathways to have a hand in the mechanism. One such possible mechanism is the increased levels of cyclic adenosine monophosphate (cAMP) as a result of interference with activation of protein kinase A (PKA), a cAMP ...
2 days ago · A mouse model of depression in comorbid with sexual dysfunction was created using the chronic unpredictable mild stress (CUMS) procedure. The therapeutic effects of CTE and its combination with FLX were assessed using depressive-like and mating behavior experiments, histopathological analysis, and hypothalamic pituitary gonadal (HPG) axis function evaluation.
4 days ago · The product labels for finasteride 1 mg (Propecia) and finasteride 5 mg (Proscar) are being revised to note that some sexual adverse effects may continue after the drugs are discontinued, the FDA announced April 11.
2 days ago · [188] [189] Finasteride is a selective inhibitor of 5α-reductase types 2 and 3, while dutasteride is an inhibitor of all three isoforms of 5α-reductase. [188] [200] [201] Finasteride can decrease circulating DHT levels by up to 70%, whereas dutasteride can decrease circulating DHT levels by up to 99%.
3 days ago · This action makes it more difficult for DHT to cause significant follicle shrinkage, slowing the progression of hair thinning and enabling better hair retention. However, minoxidil’s approach is indirect, focusing on enhancing follicle resilience rather than directly inhibiting DHT-like treatments such as finasteride.
