Search results
4 days ago · Translate the input sequence by means of an optional DNA alignment. Draw and highlight the graphical maps from Genbank and EMBL files through its feature annotations. Figure 1 shows the GUI of ApE.
1 day ago · The alignment results and contigs from the assembly were used as inputs for LACHESIS ... Primers that hybridized to the gDNA flanking the insert were designed using Primer3 Software ...
1 day ago · … A primer, as related to genomics, is a short single-stranded DNA fragment used in certain laboratory techniques, such as the polymerase chain reaction (PCR). In the PCR method, a pair of primers hybridizes with the sample DNA and defines the region that will be amplified, resulting in millions and millions of copies in a very short timeframe.
19 hours ago · Results were analyzed using Quantstudio Real-time PCR software. All reactions were performed in technical triplicates. Relative expression of targets was assessed by the 2-ΔΔCT method using β-actin as the housekeeping gene. Primers that spanned across exons for each target gene were designed using Primer3.
5 days ago · The MISA PERL script takes a genomic sequence as input and identifies all the SSRs in the sequence. The script can also classify SSRs based on their size and motifs. Both compound SSRs or repeats close to one another, and perfect SSRs where each repeat follows the preceding one without a gap, can be counted and distributed using MISA.
1 day ago · Using the template sequence as input, the analogs were identified with the maximum score and homology match in the PDB database. The best 3D structures were then selected and refined using the ModRefiner program (Xu and Zhang 2011). The visualization of the 3D protein structure and its ligand-binding sites was performed using Discovery Studio v ...
ARC-SV enables highly accurate detection and characterization of localized complex rearrangements of multiple DNA segments. Applying ARC-SV across human populations and brain cohorts uncovers connections between complex structural variantion and human-specific evolution, neural genes, and major psychiatric disorders.
