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Apr 7, 2022 · D.P. Yun, Y.Q. Wang, D.L. Meng, Y.Y. Ji, J.X. Chen, H.Y. Chen, D.R. Lu Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma Oncol.
View Baoguang Chen’s profile on LinkedIn, a professional community of 1 billion members. Senior Engineer at SP Group · Experience: SP Group · Education: National University of Singapore ·...
Transcriptional and epigenetic decoding of the microglial aging process. A three-round depletion–repopulation (3xDR) model is developed to study aged microglia in non-aged brain, giving insights into the molecular mechanism underlyingmicroglia aging. Expand.
Dec 12, 2023 · Different functional regions of brain are fundamental for basic neurophysiological activities. However, the regional specification remains largely unexplored during human brain development. Here, by combining spatial transcriptomics (scStereo-seq) and scRNA-seq, we built a spatiotemporal developmental atlas of multiple human brain regions from ...
Apr 7, 2022 · Abstract. Region-related heterogeneity and state transitions of microglia are important for brain development and neurological pathogenesis. However, regional specialization and state transition in microglia during early human CNS development remain unclear.
A single-cell transcriptomic atlas of human microglia from distinct brain regions. Neuronal gene-enriched microglia dynamically appear in the early CNS development. Immune-related microglia are regionally specialized after intermediate stages. Comparison of human and mouse microglia across species. Li et al., 2022, Cell Stem Cell , 620–634.
Dec 21, 2023 · However, the regional specification remains largely unexplored during human brain development. Here, by combining spatial transcriptomics (scStereo-seq) and scRNA-seq, we built a spatiotemporal developmental atlas of multiple human brain regions from 6-23 gestational weeks (GWs).
