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  1. A necrotizing soft tissue infection can destroy skin, muscle, and other soft tissues. If untreated, it may lead to amputation of major parts of the body, kidney failure and a high risk of death. Can a necrotizing soft tissue infection be prevented?

  2. Necrotizing soft-tissue infection is typically caused by a mixture of aerobic and anaerobic organisms that cause necrosis of subcutaneous tissue, usually including the fascia. This infection most commonly affects the extremities and perineum.

  3. Feb 27, 2024 · Necrotizing soft tissue infections (NSTIs) include necrotizing forms of fasciitis, myositis, and cellulitis . These infections are characterized clinically by fulminant tissue destruction, systemic signs of toxicity, and high mortality.

  4. Dec 7, 2017 · This and other necrotizing soft-tissue infections have multiple causes, risk factors, anatomical locations, and pathogenic mechanisms, but all such infections result in widespread tissue...

  5. A necrotizing soft tissue infection is a serious, life-threatening condition. It can destroy skin, muscle, and other soft tissues. A wound infection that is very painful, hot, draining a gray liquid, or accompanied by a high fever or other systemic symptoms needs care right away.

  6. Mar 1, 2007 · Necrotizing soft-tissue infections (NSTIs) are infrequent but highly lethal infections. They can be defined as infections of any of the layers within the soft tissue compartment (dermis, subcutaneous tissue, superficial fascia, deep fascia, or muscle) that are associated with necrotizing changes.

  7. Necrotizing soft tissue infection is typically caused by a mixture of aerobic and anaerobic organisms that cause necrosis of subcutaneous tissue, usually including the fascia. This infection most commonly affects the extremities and perineum.