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  1. Since organogenesis starts 3 to 5 weeks post-conception, it was felt that radiation exposure in early pregnancy couldn't result in malformation. Based on this, it was suggested to do away with the 10-day rule and replace it with a 28-day rule.

  2. The 28-day rule replaced the 10-day rule introduced in 1986, but there is evidence2,3 that the incidence of childhood cancer may be increased slightly following in utero irradiation before a period has been missed.

  3. The LMP refers to the first day of the last menstrual period. Women are asked for their date of LMP to confirm the status of pregnancy.

  4. This practice is commonly known as 28 Day Rule. In 1993, the NRPB published its latest statement on diagnostic medical exposure to ionising radiation during pregnancy4.

  5. Based on the knowledge of the variable radiation dose of different examinations and organogenesis, the “10-day and 28-day rules” are used whenever possible to confine exposure of women in the reproductive age to ionizing radiation to within these days following the onset of menstruation.

  6. Feb 28, 2017 · These rules apply to patients with a regular cycle length of 28 days and should be modified according to cycle length (21, 22). Despite the potential benefits of applying this rule, it creates some difficulty scheduling diagnostic tests; therefore, it is no longer applied in most radiology centers . B) What to do?

  7. Sep 18, 2020 · The 28-day rule is utilized as a precautionary measure for irradiating the fetus at an early stage of conception for abdominal and pelvic radiography. There is a...

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