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Furthermore, in fetal acid-base studies it is of interest to evaluate the correlation of clinical parameters (e.g. the APGAR score and the fetal heart frequency (FHF)) to the spectrum of these four metabolic acid-base variables, the "base excess family" (Table I). Therefore the question must arise: Which base excess should preferably be used?
We learn here that the concept of base excess was developed in 1958 by two Danish clinical biochemist pioneers of blood gas analysis, Poul Astrup and Ole Siggaard-Andersen, on the basis of in vitro human-blood-titration experiments. The aim of their experiments was to develop an index (they called it base excess) to quantify the (non ...
May 10, 2023 · Thus, base deficit and base excess are used interchangeably. Normal base excess values range from -3 to +3. Therefore, base excess of -5 indicates metabolic acidosis, whereas +5 indicates metabolic alkalosis. Base excess values are frequently used in critically ill patients to analyze acid-base disturbance (9).
The meaning of the base excess value is that it is a strong indicator of the metabolic component of acid-base balance. A high positive level, in other words a level greater than positive 2, indicates metabolic alkalosis. This means we have extra base in our blood. Most commonly this is caused by an excess of bicarb in the blood.
Aug 3, 2022 · ABG = arterial blood gas. pH, PaO2 & PaCO2 are all directly measured. HCO3-, base excess, SaO2 are derived. PaO2. PaO2 = partial pressure (tension) of O2 in arterial blood. Oxygen Tension Methods. oxygen (Clarke’s) electrode: amount of O2 producing a voltage. transcutaneous electrodes. fluorescence-based blood gas analysis: filtration of ...
May 19, 2024 · A deficit of bicarbonate and other bases indicates metabolic acidosis. Alternatively, when there is an increase in bicarbonates present, then metabolic alkalosis results. BE (Base Excess) BE. Base excess or BE value is routinely checked with HCO 3 value. A base excess of less than –2 is acidosis and greater than +2 is alkalosis.
Sep 6, 2015 · Standard base excess is the concentration of titrable base when the blood is titrated back to a normal plasma pH of 7.40, at a normal pCO2 ( 40 mmHg) and 37° C, at the actual oxygen saturation, AND at an "anaemic" haemoglobin concentration, to account for the buffering of extravascular fluid by haemoglobin. It is reported as cBase(Ecf), to reflect the fact that the entirety of the ...
