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Sep 29, 2018 · Side effects of artemisinin. Artemisinin can be taken orally, injected into your muscle, or inserted into the rectum as a suppository. This extract is associated with few side effects, but it ...
Artemisinin adalah salah satu jenis obat antimalaria. Pembuatan artemisinin berkaitan dengan wabah malaria yang menimpa para tentara Amerika Serikat dan Vietnam selama berlangsungnya Perang Vietnam. Negara pelopor untuk penemuan, penelitian dan pembuatan artemisinin adalah Tiongkok. Artemisinin ditemukan pada tahun 1972 dari spesies tumbuhan ...
Nov 18, 2022 · Malaria: Artemisinin partial resistance. 18 November 2022 | Q&A. Efficacious antimalarial medicines are critical to malaria control and elimination. Continuous monitoring of their efficacy is needed to inform treatment policies in malaria-endemic countries, and to ensure early detection of, and response to, drug resistance.
Artemisinin derivative; rapidly metabolized to active metabolite, dihydroartemisinin (DHA) Artesunate and DHA, like other artemisinins, contain an endoperoxide bridge that is activated by heme iron leading to oxidative stress, inhibition of protein and nucleic acid synthesis, ultrastructural changes, and decreased parasite growth and survival
Dec 31, 2014 · Artemisinin has been widely used for the treatment of malaria for the past two decades . Additionally, artemisinin is known to have antibacterial, antifungal, antileishmanial, antioxidant, antitumor, and anti-inflammatory activity [ 5 , 6 , 7 ].
Sep 8, 2021 · Figure 1 Artemisinin and its derivatives on both adaptive and innate immune cells. Artemisinin and its derivatives have the capacity to regulate expressions of proinflammatory and anti-inflammatory cytokines, the frequency and activation of T helper and B cells, and the responsiveness of macrophages, DCs, neutrophils, mast cells and MDSCs. “↓“ denotes “enhancing” while “⊥ ...
Feb 5, 2023 · Artemisinin is the crucial ingredient of artemisia annua, a traditional Chinese medicine used for the therapy of malaria in China for hundreds of years. In recent years, the anticancer properties of artemisinin and its derivatives have also been reported. This review has summarized the research and development of artemisinin and its derivatives ...
