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  1. Kenneth R. Chien (born 1951) [1] is an American doctor and medical scientist [2] who has been a research director at Karolinska Institute, in Stockholm, since 2013. [3]

  2. Apr 18, 2024 · The work of the Chien lab has led to the identification of a high-resolution atlas of the progenitor cells that build the human heart, as well as the factors that control their fate, using multiple model systems and core technology platforms. Part of the Department of Cell and Molecular Biology. Start.

  3. Professor of Cardiovascular Research. Articles. Article: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 2024;32 (2):101225. Endovascular transplantation of mRNA-enhanced mesenchymal stromal cells results in superior therapeutic protein expression in swine heart.

  4. Articles 1–20. ‪Dept of Cell and Molecular Biology, Karolinska Institutet‬ - ‪‪Cited by 74,889‬‬ - ‪Heart Disease‬ - ‪Stem Cells‬ - ‪Regenerative Biology and Medicine‬ - ‪Biotechnology‬.

  5. Dec 6, 2021 · K.R.C. is an advisor and chair of the External Science Panel for AstraZeneca and a member of the Karolinska Institutet/AstraZeneca Integrated Cardio Metabolic Center in Huddinge, and receives...

  6. Nov 3, 2022 · Kenneth R. Chien. Nature Biotechnology 40, 15861600 (2022) Cite this article. 86k Accesses. 171 Citations. 452 Altmetric. Metrics. Abstract. The extraordinary success of mRNA...

  7. The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19) has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical trials of mRNA therapeutics include studies of paracrine vascular endothelial growth factor (VEGF) mRNA for heart failure ….