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Biography. Parkinson's disease (PD) is one of the most common of the neurodegenerative disorders, affecting 1-2% of the population worldwide. Multiple lines of evidence place mitochondrial dysfunction as a central player in the pathogenesis of sporadic PD, and studies of genes associated with familial PD demonstrate convergent pathways ...
Michael’s work focuses on autophagy and mitochondrial quality control. The lab uses multiple imaging modalities, including AI-directed volumetric electron microscopy, combined with gene editing and biochemistry to understand the intricate mechanisms of mitophagy and mitochondrial quality control.
Michael Lazarou via Europe PubMed Central. Autophagy promotes cell survival by maintaining NAD levels. Developmental cell. 2022-11 | Journal article. DOI: 10.1016/j.devcel.2022.10.008.
Dec 11, 2019 · The Monash BDI's Dr Michael Lazarou was recently highlighted in the Journal of Cell Biology. The article covers Dr Lazarou's background and what first sparked his interest in mitochondria and autophagy, his current research focus and what drives him in his work.
Walter and Eliza Hall Institute of Medical Research, co-affiliated with Monash University - Cited by 10,337 - Parkinson's disease and mitochondrial quality control through autophagy
Dec 12, 2019 · Michael Lazarou. What first sparked your interest in mitochondria and autophagy? The first time you see fluorescently labeled mitochondria in live cells under the microscope you think, “Wow!”
Nov 19, 2019 · Michael Lazarou: Building a body of research. Marie Anne O’Donnell. Author and Article Information. J Cell Biol (2019) 218 (12): 3881–3882. https://doi.org/10.1083/jcb.201911052. Standard View. PDF. Share. Tools. Lazarou investigates the relationship between mitochondria and autophagy.
