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Dermatofibroma is a common benign tumour also known as fibrous histiocytoma. There is debate as to whether dermatofibroma has a reactive or neoplastic origin. The clinical lesion is a firm tan-brown nodule most commonly found on the legs. A number of histological variants exist. Histology of dermatofibroma.
Mar 18, 2013 · Dermatofibroma, also known as fibrous histiocytoma, is one of the most common cutaneous soft-tissue lesions, accounting for approximately 3% of skin lesion specimens received by dermatopathology laboratories. 1 If the classical clinical and pathologic features are present the diagnosis is usually straightforward.
Dermatofibroma, abbreviated DF, is a common benign skin lesion. It is also known as benign fibrous histiocytoma and fibrous histiocytoma . Contents. 1 General. 2 Microscopic. 2.1 Subtypes. 2.1.1 Cellular dermatofibroma. 2.2 Epithelioid cell histiocytoma. 3 IHC. 4 Sign out. 4.1 Micro. 5 See also. 6 References. General.
Feb 29, 2024 · Dermatofibroma, also known as fibrous histiocytoma, is a common, benign, cutaneous soft-tissue lesion characterized by firm subcutaneous nodules, typically measuring 1 cm or less in diameter. Dermatofibromas are commonly found on the extremities and are prevalent across all age groups.
Sep 14, 2023 · PATHOGENESIS. The exact pathogenesis of dermatofibromas is debated and unknown. Most dermatofibromas are thought to be a reactive process secondary to local trauma including, but not limited to, insect bites, puncture wounds due to splinters, and ingrown hairs.
The pathology of dermatofibroma shows whirling fascicles of spindle cell proliferation with excessive collagen deposition in the dermis. There are many pathological variants including: cellular
Dermatofibroma (cutaneous fibrous histiocytoma) represents a common benign mesenchymal tumor, and numerous morphological variants have been described. Some variants of dermatofibroma are characterized by an increased risk of local recurrences, and there are a few reported metastasizing cases.