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10 Jul 2023 · DKA is a state of a relative or absolute insulin deficiency that is worsened by hyperglycemia, dehydration, and acidosis. In most cases, the trigger is an infection, new-onset diabetes, or lack of compliance with treatment.
4 Okt 2020 · Abstract. Introduction: Diabetic ketoacidosis (DKA) is a complication of hyperglycemia. Through this study we plan to study the clinical features of DKA and precipitating factors responsible for DKA in type 1 and type 2 diabetes.
3 Nov 2020 · Diabetic Ketoacidosis (DKA) potentially life-threatening complication of diabetes mellitus resulting from the consequences of insulin deficiency. Diagnostic criteria. pH < 7.3; ketosis (ketonemia or ketonuria) HCO3 <15 mmol/L due to high anion gap metabolic acidosis (HAGMA) hyperglycemia (may be mild; euglycemic DKA can occur) PATHOGENESIS
Pathophysiology of DKA Insulin deficiency and an increase in counterregulatory hormones ( glucagon , catecholamines, cortisol ) causes the body to metabolize triglycerides and amino acids instead of glucose for energy.
23 Mei 2023 · This comprehensive review compiles and evaluates recurrent and dominant topics discussed in the literature regarding the epidemiology, pathophysiology, and emergent therapy for patients with diabetic ketoacidosis, a complication of type 1 diabetes (T1DM) and less frequently type 2 diabetes (T2DM).
Pathophysiology of DKA Figure 1: Pathophysiology of diabetic ketoacidosis. DKA is the result of a critical relative or absolute deficiency of insulin, resulting in intracellular starvation of insulin-dependent tissues (muscle, liver, adipose), stimulating the release of the counter-regulatory hormones glucagon, catecholamines, cortisol,
28 Okt 2015 · What is DKA? Diabetic ketoacidosis (DKA) is an extreme metabolic state caused by insulin deficiency. The breakdown of fatty acids (lipolysis) produces ketone bodies (ketogenesis), which are acidic. Acidosis occurs when ketone levels exceed the body’s buffering capacity (figure ⇓ ). 1 2.
