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  1. Jul 26, 2023 · Acyclovir treatment is best started within 72 hours of symptom onset (ie, rash, blisters, tingling, burning) and most effective if started within 48 hours of symptom onset. Take acyclovir for the duration prescribed by your doctor, even if your symptoms improve.

  2. Feb 16, 2024 · Antiviral treatment should be started as soon as possible, as it is most effective when started within 72 hours after the shingles rash appears. After this time, antiviral medications may still be helpful if new blisters are appearing.

  3. Nov 15, 2017 · Herpes zoster can be treated with acyclovir, valacyclovir, or famciclovir, ideally within 72 hours of the development of the rash.

  4. Nov 24, 2010 · A short course of acyclovir therapy (800 mg five times a day for 4 days) showed a similar efficacy for patients presenting with rash duration for >72 hours and for duration <72 hours.

  5. 3 days ago · In clinical practice, however, these second-generation antiviral agents might be more effective than acyclovir because patients are more likely to comply with the treatment regimen (3 rather than 5 daily doses). The efficacy of antiviral medication initiated more than 72 hours after the onset of skin rash has never been confirmed.

  6. Jul 24, 2023 · Varicella-zoster immune globulin is the preferred therapy for postexposure prophylaxis; oral antiviral therapy may be used when passive immunization is not possible; if antiviral therapy is used, varicella vaccines should not be given for at least 72 hours following last dose.

  7. Jan 1, 2023 · However, even after 72 hours, the initiation of antivirals is suggested for all immunocompromised patients, in cases of new vesicles appearing in patients with significant complications or at risk of developing complications, and those with disseminated lesions invading the eyes and ears [1,8,26,28].