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  1. Sep 12, 2024 · The Hunter Criteria are the most accurate diagnostic criteria; a patient must have the presence of a serotonergic agent and meet one of the following conditions (see 'Diagnosis and diagnostic criteria' above):

  2. We recently developed diagnostic criteria for serotonin toxicity — the Hunter Serotonin Toxicity Criteria (HSTC) — by studying large numbers of patients ingesting serotonergic agents in over-dose. The HSTC can be used to determine whether a patient who has taken an overdose has significant serotonin toxicity (Box 4).

  3. May 1, 2010 · Diagnosis is made using the Hunter Serotonin Toxicity Criteria, which require the presence of one of the following classical features or groups of features: spontaneous clonus; inducible...

  4. These new criteria were simpler, more sensitive (84% vs. 75%) and more specific (97% vs. 96%) than Sternbach's criteria. Discussion: These redefined criteria for serotonin toxicity should be more sensitive to serotonin toxicity and less likely to yield false positives.

  5. Hunter Area Toxicology Service (HATS) following an overdose of a serotonergic drug from January 1987 to November 2002 (n¼2222). Main out-comes were: diagnosis of serotonin toxicity by

  6. The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity. BACKGROUND: There are difficulties with the diagnosis of serotonin toxicity, particularly with the use of Sternbach’s criteria.

  7. Jun 26, 2024 · Diagnosing serotonin toxicity presents challenges as there are no definitive criteria. This review delves into the pathophysiology, incidence, clinical assessment and management of serotonin toxicity, stressing the significance of promptly recognizing and managing severe cases.