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  1. In fact, coagulase-negative staphylococci are the most common blood culture contaminants, typically representing 70% to 80% of all contaminated blood cultures (25, 92, 105, 113, 125).

  2. May 24, 2022 · The most common contaminants of blood cultures are the coagulase-negative Staphylococci, microflora found on the skin, most likely due to insufficient antiseptic technique. However, these bacteria can cause severe bloodstream infections, especially in immunocompromised patients, making it important but difficult to differentiate a contaminated ...

  3. Apr 3, 2018 · Blood culture (BC) remains the reference standard for the diagnosis of bloodstream infections (BSIs), but contaminations represent up to 50% of positive BCs [1,2].

  4. Jul 20, 2020 · There are several untoward clinical consequences of contaminated blood cultures, the most obvious of which is increased antibiotic exposure. Bates et al. found that intravenous antibiotic charges were 39% higher for contaminant blood culture episodes than among culture-negative patients .

  5. Dec 5, 2023 · For determining CLABSI rates, the CDC provides a list of organisms considered “common commensals” (19). This list is very extensive (>500 microorganisms), making the use of this list cumbersome for certain methods of tracking and estimation of overall BCC rates for laboratory purposes.

  6. Blood culture contamination is common, constituting up to half of all positive blood cultures at some institutions. The identity of the organism isolated can help in determining if the culture is contaminated, as some organisms rarely cause BSIs. The number of blood cultures that yield a particular organism can help predict true infections.

  7. Blood culture contamination can lead to unnecessary antibiotic exposure and prolonged hospitalization. Learn how to track, report, and reduce contamination rates with infection control and antibiotic stewardship programs.