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  1. Jun 24, 2023 · Asthma is primarily involved in the bronchial tree, with its primary job to distribute air throughout the lungs until reaching the alveolar sacs. The bronchi stem from the end of the trachea, which divides into left and right bronchi.

  2. This section presents a definition of asthma, a description of the processes on which that definition is based—the pathophysiology and pathogenesis of asthma, and the natural history of asthma. Asthma is a common chronic disorder of the airways that involves a complex interaction of airflow obstruction, bronchial hyperresponsiveness and an ...

  3. Jun 14, 2024 · The pathophysiology of asthma refers to the changes that occur in the airways and lungs that lead to asthma symptoms. Understanding the pathophysiology can help with targeting asthma treatment....

  4. Asthma is a common pulmonary condition defined by chronic inflammation of respiratory tubes, tightening of respiratory smooth muscle, and episodes of bronchoconstriction. [1] . The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America. [1] .

  5. May 6, 2024 · Key facts. Asthma is a major noncommunicable disease (NCD), affecting both children and adults, and is the most common chronic disease among children. Inflammation and narrowing of the small airways in the lungs cause asthma symptoms, which can be any combination of cough, wheeze, shortness of breath and chest tightness.

  6. May 3, 2024 · Pathophysiology. Asthma is a syndrome characterized by diverse underlying mechanisms and involves intricate interactions among inflammatory and resident airway cells. These mechanisms lead to airway inflammation, intermittent airflow obstruction, and bronchial hyperresponsiveness (see Image. Pathophysiology of Asthma). Airway Inflammation

  7. Asthma is a disease of diffuse airway inflammation caused by a variety of triggering stimuli resulting in partially or completely reversible bronchoconstriction. Symptoms and signs include dyspnea, chest tightness, cough, and wheezing. The diagnosis is based on history, physical examination, and pulmonary function tests.

  8. Feb 1, 2001 · To comprehend the pathogenetic mechanisms underlying the many variants of asthma, it is essential to identify factors that initiate, intensify, and modulate the inflammatory response of the...

  9. Feb 9, 2022 · The inflammatory, physiologic, and structural factors that contribute to the pathogenesis of asthma will be reviewed here, focusing on aspects that aid in the understanding of the clinical presentation of asthma and its treatment.

  10. Apr 6, 2024 · Identify and avoid asthma triggers. A number of outdoor allergens and irritants — ranging from pollen and mold to cold air and air pollution — can trigger asthma attacks. Find out what causes or worsens your asthma, and take steps to avoid those triggers. Monitor your breathing.

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