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(+)-artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial and a plant metabolite.
- Artemisinins: their growing importance in medicine - PMC
Chemical structures of artemisinins. Artemisinin (a)...
- Biological Actions of Artemisinin: Insights from Medicinal Chemistry ...
Artemisinin was proposed to have a structure similar to that...
- Artemisinins: their growing importance in medicine - PMC
Artemisinin (/ ˌ ɑːr t ɪ ˈ m iː s ɪ n ɪ n /) and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum. It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her discovery.
Chemical structures of artemisinins. Artemisinin (a) isolated in crystalline form in 1973 from Artemisia annua and derivatives dihydroartemisinin (DHA) (b), artemether (c), artesunate (d) and arteether (f) were first prepared by Chinese scientists in the 1970s [1].
Feb 1, 2019 · Artemisinin (and its various derivatives, which we will refer to collectively as “artemisinin” unless otherwise specified) is a sesquiterpene lactone compound (Fig. 1) with a unique chemical structure derived from the sweet wormwood plant, Artemisia annua L. (Fig. 2).
Aug 27, 2012 · At the end of 1975, its unique chemical structure was elucidated, as a sesquiterpene lactone bearing a peroxy group, quite different from that of all known antimalarial drugs 3.
Mar 8, 2010 · Artemisinin was proposed to have a structure similar to that of thapsigargin (Figure 1 i), which specifically binds and inhibits the sarcoplasmic/endoplasmic calcium ATPase (SERCA), in the absence of the endoperoxide bond.
Structure, properties, spectra, suppliers and links for: Artemisinin, qinghaosu, 63968-64-9.
