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The germinal matrix is a region in the brain where neurons and glial cells migrate during development. It is also a fragile area that can bleed and cause intraventricular hemorrhage in premature infants.
The germinal matrix (GM) is a delicate web of densely packed blood vessels and neural stem/progenitor cells (NSPCs) found adjacent to the ependymal lining of the ventricular system. There, in the thalamostriate groove, the GM generates both cortical neurons and glia.
May 29, 2020 · The germinal matrix is an embryological structure in the fetal brain which is only seen in the fetus and in premature neonates. It is the most vulnerable area of the fetal brain and associated pathology carries significant mortality and morbidity.
Aug 21, 2024 · Learn about germinal matrix hemorrhage, a common type of intracranial bleeding in premature infants. Find out the causes, risk factors, clinical presentation, pathology, classification, radiographic features, treatment and prognosis of this condition.
Jul 17, 2023 · The germinal matrix is an area of neuronal and glial proliferation, is highly vascular, and contains fragile single-cell thick vessels. It is a common site of hemorrhage in premature low-birth-weight infants with an incidence of 20 to 25%.
Jan 1, 2021 · The germinal matrix (GM) is a delicate web of densely packed blood vessels and neural stem/progenitor cells (NSPCs) found adjacent to the ependymal lining of the ventricular system. There, in the thalamostriate groove, the GM generates both cortical neurons and glia.
Germinal matrix is a transient cell layer in the developing brain that produces neurons and glial cells. It is vulnerable to hemorrhage and infarction in premature infants, which can be imaged by ultrasound, CT, and MRI.
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