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May 13, 2022 · Malignant hyperthermia is a severe reaction to certain drugs used for anesthesia. This severe reaction typically includes a dangerously high body temperature, rigid muscles or spasms, a rapid heart rate, and other symptoms.
Malignant hyperthermia is a disorder that can be considered a gene–environment interaction. In most people with malignant hyperthermia susceptibility, they have few or no symptoms unless they are exposed to a triggering agent.
Aug 17, 2023 · Malignant hyperthermia (MH) is a hereditary disorder of skeletal muscle that classically presents as a hypermetabolic response to halogenated anesthetic gasses and/or the depolarizing muscle relaxant succinylcholine.
Overview. What is malignant hyperthermia? Malignant hyperthermia is a genetic disease that causes a life-threatening reaction to certain anesthesia medications. The disorder usually runs in families and is treatable. General anesthesia allows a person to undergo surgery without awareness.
Jan 6, 2022 · Malignant hyperthermia is a potentially lethal syndrome usually triggered by inhalation anaesthetics or succinylcholine (suxamethonium). The underlying genetic susceptibility is most often due to a range of autosomal-dominant mutations in RYR1.
May 13, 2022 · Malignant hyperthermia is diagnosed based on signs and symptoms, monitoring during and immediately after anesthesia, and lab tests to identify complications. Susceptibility testing Testing to find out if you're at increased risk of malignant hyperthermia (susceptibility testing) may be recommended if you have risk factors.
Jul 24, 2020 · Malignant hyperthermia (MH) is a life-threatening clinical syndrome of hypermetabolism involving the skeletal muscle. It is triggered in susceptible individuals primarily by the...
