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May 29, 2024 · Morning glory sign of progressive supranuclear palsy (PSP) and multisystem atrophy, not to be confused with morning glory syndrome, refers to the appearance of the midbrain on axial imaging 1. Graphically this is identified on an axial image at the level of the midbrain by drawing 1: . a horizontal line drawn through the edge of the posterior ...
May 30, 2024 · Morning glory sign is a radiographic feature of progressive supranuclear palsy (PSP), a neurodegenerative disease with no cure. It is the loss of the lateral convex margin of the tegmentum of midbrain, seen on axial imaging.
Sep 1, 2018 · The hummingbird sign and the morning glory sign are MRI features of midbrain pathology that can help distinguish progressive supranuclear palsy (PSP) from other parkinsonian disorders. Learn about their diagnostic accuracy, sensitivity, specificity and inter-rater reliability in a large cohort of patients and healthy controls.
Jun 5, 2023 · The “morning glory” sign refers to a specific pattern of midbrain atrophy, which leads to a concave aspect of the lateral margins of the midbrain tegmentum on axial images. This sign was found in four out of five patients diagnosed with PSP, but in only 1 out of 37 patients diagnosed with MSA or PD, and was shown to correlate with the ...
Progressive supranuclear palsy is a rare, degenerative central nervous system disorder that progressively impairs voluntary eye movements and causes bradykinesia, muscular rigidity with progressive axial dystonia, pseudobulbar palsy, and dementia. Diagnosis is clinical.
Apr 6, 2017 · On the axial image, reduced anteroposterior diameter of the midbrain at the level of the superior colliculi is known as the “morning glory sign” or “Mickey mouse sign” [29, 30]. These signs, indicative of midbrain atrophy, are clinically useful to differentiate PSP from other parkinsonian syndromes [ 9 ].
Aug 1, 2024 · These pathological changes mainly affect the brainstem and the basal ganglia, resulting in distinctive MRI features, such as the hummingbird and morning glory signs. PSP shows clinical heterogeneity and presents as different phenotypes, the most classical of which is Richardson's syndrome (PSP-RS).
