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  1. Jan 7, 2022 · Health Library / Treatments & Procedures / Calcium Channel Blockers. Calcium channel blockers are a group of medications that limit how your body uses calcium. By slowing down how your cells use calcium, these medications can lower your blood pressure, prevent heart rhythm problems and more.

  2. Nov 1, 2023 · Calcium channel blockers (CCBs) are split into two categories, dihydropyridines (DHP), such as amlodipine and nicardipine, and non-dihydropyridines (non-DHP), such as verapamil and diltiazem. While these two drug classes are both CCBs, there are some key similarities and differences that are important to take into consideration when prescribing ...

  3. Nondihydropyridines work by blocking the calcium channels present in the heart muscle and reduce the influx of calcium into cardiac muscle cells (myocytes), leading to a decrease in the heart rate and contractions of the heart muscle.

  4. Feb 22, 2024 · Calcium channel blockers (CCBs), also known as calcium channel antagonists, have been approved by the US Food and Drug Administration (FDA) and are widely used to treat various conditions such as hypertension, coronary heart disease, and chronic stable angina.

  5. Nov 8, 2023 · There are two different types of calcium channel blockers, known as dihydropyridines and nondihydropyridines. Dihydropyridines target a specific type of calcium channel in the body. They cause...

  6. Dec 19, 2022 · Calcium channel blockers (CCBs) are common drugs that treat high blood pressure, irregular heartbeats, and some causes of chest pain. They help reduce the risk of cardiovascular events like heart attacks and strokes. These medications are also called calcium channel antagonists.

  7. Aug 28, 2023 · Diltiazem is an oral and parenteral non-dihydropyridine calcium channel blocker. It is used in many clinical scenarios as an antihypertensive, anti-arrhythmic, and anti-anginal. FDA-approved indications include atrial arrhythmia, hypertension, paroxysmal supraventricular tachycardia, and chronic stable angina.