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Base excess (BE) was introduced by Siggaard-Andersen in 1960 as an answer to the forty-year-long quest for a reliable, stand-alone marker of metabolic acidosis/alka-losis, independent from co-existing respiratory derange-ments, and able to quantify the severity of the disorder [1]. Previously, several parameters had been examined.
May 21, 2019 · Base Excess (BE) in an ABG. “The base excess is another surrogate marker of metabolic acidosis or alkalosis. A high base excess (> +2mmol/L) indicates that there is a higher than normal amount of HCO 3- in the blood, which may be due to a primary metabolic alkalosis or a compensated respiratory acidosis. A low base excess (< -2mmol/L ...
May 11, 2024 · A parameter which indicates the acid-base balance in the body. Base excess is defined as the amount of protons (H+ ions) required to return the pH of blood to 7.35 if the partial pressure of carbon dioxide was adjusted to normal. Base excess is affected by blood lactate, with which it has a high correlation, and organic acids which accumulate ...
Apr 11, 2018 · The low pH, the high Pa co2, and a standard base excess above 2 mmol per liter suggest a chronic respiratory acidosis ( Table 1 ). One thus expects the standard base excess, calculated as 0.4× ...
Aug 6, 2015 · The "Base Excess" is the amount of acid or base required to titrate a blood sample (of whole blood) to a pH of 7.40, at standard temperature and pressure, with a standard PaCO2 of 40mmHg. The "Standard Base Excess" is different because it uses extracellular fluid rather than whole blood. Given that extracellular fluid is a fairly heterogeneous slurry which is inconvenient to sample, the ABG ...
May 10, 2023 · Thus, base deficit and base excess are used interchangeably. Normal base excess values range from -3 to +3. Therefore, base excess of -5 indicates metabolic acidosis, whereas +5 indicates metabolic alkalosis. Base excess values are frequently used in critically ill patients to analyze acid-base disturbance (9).
Furthermore, in fetal acid-base studies it is of interest to evaluate the correlation of clinical parameters (e.g. the APGAR score and the fetal heart frequency (FHF)) to the spectrum of these four metabolic acid-base variables, the "base excess family" (Table I). Therefore the question must arise: Which base excess should preferably be used?
